PUBLICATIONS
Fitzgerald H., Bonin,J.L, Sadhu S., Lipscomb M., Biswas N., Decker C., Nabage M., Ramos R.B., Duarte, G.A., Marinello M., Chen,A., Aydin, H.B., Mena, A.H., Gilliard K.,, Spite, M., DiPersio, C.M., Adam, A., MacNamara, K.C., Fredman, G. Resolvin D2-GPR18 Enhances Bone Marrow Function and Limits Steatosis and Hepatic Collagen Accumulation in Aging. Am J Pathol. 2023 Sep 16:S0002-9440(23)00322-X. doi: 10.1016/j.ajpath.2023.08.011.
Sadhu S, Decker C, Sansbury BE, Marinello M, Seyfried A, Howard J, Mori M, Hosseini Z, Arunachalam T, Finn AV, Lamar JM, Jourd'heuil D, Guo L, MacNamara KC, Spite M, Fredman G. Radiation-Induced Macrophage Senescence Impairs Resolution Programs and Drives Cardiovascular Inflammation. J Immunol. 2021 Oct 1;207(7):1812-1823. doi: 10.4049/jimmunol.2100284. Epub 2021 Aug 30. (PMID: 34462312).
Hosseini Z, Marinello M, Decker C, Sansbury BE, Sadhu S. Gerlach BD, Ramos RB, Adam AP, Spite M and Fredman G. Resolvin D1 enhances necroptotic cell clearance through promoting macrophage fatty acid oxidation and oxidative phosphorylation. ATVB. 2021 Jan 21:ATVBAHA120315758. doi: 10.1161/ATVBAHA.120.315758. PMID: 33472399.
Rymut N, Heinz J, Sadhu S, Hosseini Z, Riley CO, Marinello M, Maloney J, MacNamara KC, Spite M, Fredman G. Resolvin D1 promotes efferocytosis in aging by limiting senescent cell-induced MerTK cleavage. FASEB J. 2020 Jan;34(1):597-609. doi: 10.1096/fj.201902126R. Epub 2019 Nov 26. PMID: 31914705.
Gerlach BD, Marinello M, Heinz J, Rymut N, Sansbury BE, Riley CO, Sadhu S, Hosseini Z, Kojima Y, Tang DD, Leeper NJ, Spite M, Barroso M, Rayner KJ, Fredman G. Resolvin D1 promotes the targeting and clearance of necroptotic cells. Cell Death Differ. 2019 Jun 20. doi: 10.1038/s41418-019-0370-1. (PMID:31222041)
Fredman G, Hellmann J, Proto JD, Kuriakose G, Colas RA, Dorweiler B, Connolly ES, Solomon R, Jones DM, Heyer EJ, Spite M and Tabas I. An imbalance between specialized pro-resolving lipid mediators and pro-inflammatory leukotrienes promotes instability of atherosclerotic plaques. 2016. Nat Commun. 7:12859 doi:10.1038/ncomms12859
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